Monday, September 28, 2020

Trump may take Biden for granted and .. "something always happens" - watching Inovio, I "donno".

 

Market Talk

Since I  coined the term "the Biden effect" the overall market has seriously corrected with the Dow off over 2600 pts at times .  I suspect that at points during the next 36 days to the Nov 3 election, every time the balance seems to shift to a socialist Democrat victory - the overall market may just fade.  It will no doubt have bouts of optimism and dead cat bounces, but with a close election uncertainty will prevail and the market dislikes uncertainty.  High Taxes, tax and spend notions and socialism will change America as we know it.  Look at Venezuela.  Once one of the richest countries in Capitalism, that fell for socialism and is now a dictatorship called a Federal executive power. Once the richest country in South America now left poor starting with socialism leading to dictatorship.  Free stuff is not free.

Tomorrow night's debate may bring some over to one side or the other, but as an informal poll many people I have talked to favor Biden. Just for "a change".  Many do not seem aware of the Democrats progressive socialist agenda that is also backed by Marxist communists. There is polar chasm in the country regarding politics where each side has hate and disgust for the other. One thing seems clear to this observer is that the Democrats are pulling out all stops and mobilizing to defeat Trump.  

As far as tomorrow's debate it seems like a prize fight is coming.  I have my view that Trump may be taking Biden for granted.  I suspect that Biden will surprise and perform better than expected.  If Trump comes off arrogant like George Bush senior made the mistake against Bill Clinton, Trump will lose the debate.

So as far as today's market , maybe the market may rally thinking Trump will outperform Biden tomorrow night.  I am not so sure.  If Biden does well, better than the lower expectations (that the Trump campaign have put out there), I am suspecting the Biden effect may just take the market lower after any rally.
 
 
 Stock Talk
 

This morning, Inovio announced there is a technical hold on the INO4800 P2/3 trials.  It is related to FDA questions on the Cellectra device used to help deliver the DNA vaccine. It is NOT about any adverse effects of patients in the Phase 1 trial.  Inovio is conducting other trials with Cellectra device and ALL other trials are NOT impacted. So WHY now, just as Phase 3 is about to start? It kind of seems politically motivated by the FDA.

The FDA has been "pumping" Moderna's  mRNA vaccine that requires super cooling. This I believe is due to reports that the NIH holds joint patents and has a vested interest in Moderna's vaccine success.  I would not take Moderna's vaccine or Pfizer's mRNA vaccine with high fevers and fatigue reported. I would not take Astra/ Oxford vaccine with NY Times reported transverse myelitis cases.  That is a neurological condition that affects the spine and can cause severe paralysis. So far, Inovio's INO4800 has no reported AE's and the reports by Inovio thus far shows a very promising immune response. But no matter, why WOULD the FDA do that?  The FDA should be investigated for Payola by short sellers.

Well, the FDA technical hold will await Inovio's response and then they the FDA has 30 days to respond. Oh boy, this falls under my saying here.. "something always happens". 

The DoD ordered $71 Million worth of Cellectras with the Pentagon  for the military.  Why now with the FDA questions?  It all makes me wonder about the FDA.  Did some short seller outfit pay somebody off?  Yep, something always happens.

http://ir.inovio.com/news-releases/news-releases-details/2020/INOVIO-Reports-FDA-Partial-Clinical-Hold-for-Planned-Phase-2--3-Trial-of-COVID-19-Vaccine-Candidate-INO-4800/default.aspx

__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

Thursday, September 17, 2020

Risk Back On - Trump Can NOT Win WITHOUT the WOMEN VOTE and Dems Don't Care about the economy for now.

 

Market Talk

 

The Title says it all man.  Today,  American Airline execs visited the White House.  They warned of big airline furloughs coming on October 1, without further relief, grants or more ppp, and closing down operations at smaller airports. Next, they are visiting Nancy Pelosi.  (Good luck with that! ).  The Dems want it all or nothing. Further, it seems the Dems prefer as much misery in the America as possible so people think - hey things are bad and vote for them! (bad move, imo).  I have coined a term for market watch - " The Biden Effect". -  and it's not a good thing for the overall market.

President Trump  had a nice day with peace treaty's between Bahrain and Israel. That was a great thing.  However, the real base of turmoil in the Middle east remains to be - Iran's leaders.  Here is my latest view on the coming election that I beleive will bear influence on the market.  Trump Can not win without the women's vote. And unfortunately, he is behind in the polls with women. His law and order stance without giving due credence to the notion that Policing techniques need improvement.  Here is an observation. many people black and white are scared and/or  angry. By Trump's insistence to keep saying "law and order" he is missing the point of dealing with the strife in people's hearts. And when you mess with hearts, you are messing with a women's wrath.  And they will vote for  a Trojan horse called "good ol' Joe" and thus allow socialism and then Marxist views with no borders on America. In short, I think at this point Biden is sadly leading over Trump.  And also, if they take Biden for granted in the debates?  big mistake.

Yesterday, the Snowflake IPO was a big hit on speculation.  However the clamor to get in Snowflake by the big players took some steam out of the other  stocks like tech stocks.  My plan is to try to find opportunity in what I see as possibly under- recognized situations, but stay with a a powder dry mode awhile. So my take should be viewed with cautious optimism but not going overboard or "betting" the farm on any particular stock.


 Stock Talk
 
In  a powder dry mode.  That said, I do like the story and game plans on Inovio and Vaxart.  But "story stocks" have to play out the story and carry through. Time and events and the old "something always happens" line can come into play along with the line -  "OBE"  or - overtaken by events.
 
Here are a few links on Vaxart (VXRT) and Inovio (INO).

 
Vaxart is taking an oral vaccine to a FDA Phase 1 clinical trial that will pass through the stomach and dissolve in the intestinal tract.  Will it be in time?  Covid 19 will likely be with us a long time in my view.
 
The recent  Inovio  Conference call points to this company eventually becoming " a disrupt-er"  in Big Pharma and the space of future cancer treatments using their DNA compounds to train the immune system to target and destroy pathogens such as Covid 19 and Cancers. That is BIG and why I am cautiously optimistic on INO stock and holding some.


If you look at the above there is a key word to take note of - eventually.  I'm in some of the above , but waiting for eventually to happen.

"someday" -  said the blind man we will see!
__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

 

Monday, September 14, 2020

Football is Back ! - lighter spirits may lift the market a few days? some INO (and VXRT?) with cautious optimism.

 

Market Talk

My previous posts have been somewhat ominous about the market as of late.  Indeed the markets have taken a hit.  However, on a day to day basis, market sentiments shifts as focus is given to different stocks.  So the weekends are a time for rest and reflection for many.  With football now on it brings a sense of normality to see our favorite teams back on the TV.  It makes us feel a little better to watch something that is separate from the polarizing politics.  I will not be surprised to see a corresponding market bounce as bargain hunters and those that experienced recent loss try to $ cost average.

Stock Talk

For example, we see stocks like Apple having a Sept 15 event where new products will be announced.  The latest rumors are it may be about new Apple watches.

I've been kind of bearish on the market outlook. However that does not mean that market bounces are off the table.  I've been correct the last few market talks.  I  maintain my overall view on "the Biden effect".   However, the market may try to bottom fish stocks that have recently dipped.

For me, I am holding "some"  Inovio (INO ) shares on hopes that the vaccine INO4800 will gain more recognition as providing a safe and effective immunity against Covid 19. That the OWS team has thus far shunned funding Inovio is a tad concerning. However, with the recent slamming of INO share level, I am in some INO shares because I think the preliminary data and events looks more than promising.

If interested, the reader is encouraged to look at Inovio's progress on INO4800 and the pipeline of cancer treatments using their DNA compounds genetically coded to illicit an immune response with targeted t cells. Look into INO and make you own decision. If becoming "bullish", I can only say tone it down to "cautious optimism"  and don't buy "too much".  There is still proving that needs to be done and DNA approach is new.

However, I will close with the theory that coded DNA creates messenger RNA cells that in turn create targeted neutralizing anti- bodies and T cells to fight pathogens and cancers..  and with that I close by saying I am in some INO because if the theory proves out it will be a  disruptive phenomena to big Pharma.  Inovio being a relative small company having such an impact could turn a hundred or so INO shares purchased near recent lows into something of significance later on.  Is that an investment or a speculation?  currently I will treat it as a spec but further affirmation could make this a longer term investment to hold  half if it doubles.

Update:  Today we see that Vaxart (VXRT) gained FDA approval to start Phase 1 trial of their oral vaccine for Covid 19. At this point, this is way behind other companies but an oral pill that passes through the stomach and reaches the mucus lining of the intestines has appeal.  There was once a pill vaccine for Polio.  Being behind the curve on the vaccine time line is a disadvantage.   However,  being a convenient pill form vaccine , if successful, could have big advantages.  VXRT is in the 6's somewhat in the lower mid range of recent trading since Covid 19 hit the world hard. Yea, it's another "spec" stock but when this stock has moved it has shown to move in a big way.

 

__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

 

Saturday, September 12, 2020

Is a Bear Market waking up on " the Biden effect" ? - Socialist democrats - yikes!

 

Market Talk

If you read my past few Market Talks,  you may note that this blog went to a powder dry - cash mode. And suddenly we now see some of market  pundits like Jim Cramer  saying the same thing.

I have coined a term here called "the Biden effect".  Now The President has stated that the market will crash if the democrats take the White House.  There are certainly indicators that it could well crash.  I have to make one point, it may start happening BEFORE the Nov 3 decision. And the pundits are saying that a close election could take months to figure out the winner - Yikes! With all the uncertainty and turmoil - who needs it? 
 
There are BIG issues at stake in this election that will determine the direction that America will take.  It goes way, way beyond personality of one or the other. The bigger effect goes into whether the fundamental principals of independent constitutional freedom and capitalism  will prevail or America will change to government controlled socialist ways.  To that I would say look at the history of Venezuela since going socialist.

For all young Americans that are leaning towards socialism,  I would suggest you to tune to AM radio host Mark Levine and hear  his message about America's history and directions. With that said, it seems like it may be a very, very close election and the democrats may be mobilizing to have a bigger impact than the last election. Free stuff winds up NOT being free.
 
My own father was a WW 2 Vet who flew 30 missions over Nazi Germany and last 2 missions were on D-Day. He had less than a 20% chance of actually surviving his tour, but his plane turned up battered with holes, but they made it. He did not take part in saving the world and America  from  tyranny and mass executions and to have America lose it's rich history, identity and borders. On that I have to agree with Trump, if no borders, we have no country. There is much as stake in this election!
 
Now without further political view, I will offer some observations that I am being  mindful of in "the market" ...
 
Wall Street Vs Main Street Phenomena:
 
For quite awhile and especially since the pandemic, there has been quite a disconnect between the market boom and Main street.  If Main street turns towards the democrats as the city folks tend to do, and they do take Nov 3, the Biden effect could indeed crash the market as main street starts  seeing what they have done. Be careful what you wish for Main street! 

The Trump disconnect:
 
When we watch Donald Trump, he goes on the attack against his opponents. Sometimes rightfully so. Since the day he has been elected, the dems have been trying to impeach him on false premises.
They "don't like him" I get that.  He can irritate the hell out of people sometimes when he speaks off the cuff with sometimes wacky statements ( so does Biden!). But Trump is somewhat misunderstood, he is trying to be humorous sometimes but it comes off bad, like the time he said he could shoot somebody and get away with it! He was trying to say he thought his people loved him so much, but man - that was wrong headed and a wacky thing to say! So I get why many think "the Donald" is a billionaire "tool" . Sometimes he is!  However, he does stand up for America and represent. He brought back steel mills and industry to America, made new deals for our farmers with China and more recently helped broker new agreements in the Middle east with Israel. Unemployment rates, before the Pandemic was at all time lows for all Americans of every ethnic.
 
I will now outline a serious flaw that Trump displays.  With the BLM movement, it seems that Trump is rightfully disturbed about the looting and disrespect for police stations and court houses and stores and businesses that has taken place in cities run by Democrat mayors and state Governors.  However, where Trump is failing to connect with many is when he constantly refers to "law and order" without addressing some of the real concerns about excessive police force . 
Modified training and means beyond "shoot to kill" practices are needed in this country.  When the police are confronted with the mentally disturbed (of all ethic groups) situations there has got to be a better protocol to take in many situations. We do not hear Trump giving much credence to the notion that police training and situational awareness need to be improved .  along with some situations could benefit from a trained worker  with the police to help handle the mentally disturbed ones.  

Now Trump's recent positions saying "Law and Order" and "let the justice system"  handle incidents where the police get caught on camera using excessive force - turns people off that may otherwise vote for him.  They are looking for a Leader in this area and Joe Biden is there and he will get their vote.  And these people, that hate Trump, do not even think about what policies come with the democrats.
 
In short, nobody is perfect especially Trump.  I point this out to say if enough people line up perceived personality grievances against Trump, many will vote democrat regardless of what bad policies for America come. 
 
 The mistake of the unaware:

The young voters today do not have quite the same values as those of us who grew up with WW2 era parents that stood up and fought (with our flag!) for America and the entire world on the beaches of Normandy and Island of Iwo Jimo.  My father and Uncles were there and they raised me to remember.  When the flag is disrespected, the ones doing so  dishonor my own people and many other Americans.

Anniversary of the flag raising at Iwo Jima - VAntage Point


The sacrifice of the greatest generation saving the world from fascist tyranny overrides all slighting of prior history that any American may believe that they are now entitled to "special treatment".  And the Antifa movement that wants to destroy American history and culture and "start over" with some twisted socialist / Marxist views?

 "Marxism is a social, political, and economic philosophy named after Karl Marx, which examines the effect of capitalism on labor, productivity, and economic development and argues for a worker revolution to overturn capitalism in favor of communism."

 Big Money may be "hunkering down"

With the recent turmoil in democrat cities like New York ( the mayor took his honeymoon in Cuba, The Governor said the President is not welcome to walk the streets in New York City?_ And yet they all desperately want federal bailouts for their state run mismanagement.

If big money is bailing out from their cities. moving back to their summer homes in the country, what are they doing with their stock market gains?  Perhaps bailing out and hunkering down for the possible new socialist America of a Bernie Sanders type government and then what after capitalism suffers?

Conclusion:

I have outlined and kind of alarmed about a phenomena I now call "the Biden effect" that may continue affecting the stock market before the election of November 3rd. This does not mean that I will not venture into the market as certain opportunity arises.  However in any stock pick , if feeling bullish, I will personally change my view to "cautious optimism".

 I do not make recommendations here.  I can only say what they say when it seems like it may be time to hunker down.  Keep some powder dry.  If buying a stock and you feel bullish change the thinking to "cautious optimism"  and don't put the farm on any one thing.

__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

Wednesday, September 9, 2020

Why I think the OWS team is failing to deliver the best Vaccine INO 4800 - Alert Trump

 

 Opinion
 
 
This is my opinion.
 
Recently Inovio put out a pr that stated that INO4800 produced immune responses against both original Covid 19 and the more recent mutation (D614G). I have not heard any of the selected vaccines reporting that. So this I say...
 
The Inovio CEO should be heading back to the White House tomorrow knocking on Trump's door to let him know how his Operation Warp speed (ows) advisors have failed to recognize that mRNA is created BY DNA  and INO4800 tests show it adapts DNA with the genetic code to recognize Covid 19 AND  the recent mutant and to then send the targeted mRNA with the exact instructions and antibodies and T Cells to defeat corona in the body.

I now believe Trump has been mislead by Fauci and the Ows team because they have a not invented here syndrome that is going to result in delivering non-durable unstable deep frozen CRAP (Moderna and Pfizer's) to the public.

"INO-4800 showed durable antibody and T cell responses in rhesus macaques for 4 months
- INO-4800 is the only vaccine to demonstrate long-term protection in non-human primates challenged with SARS-CoV-2 virus 13 weeks from vaccination
- Memory T and B cell responses resulted in reduced viral loads and faster viral clearance in macaques' lungs and nasal passages
- INO-4800 vaccination generated antibodies neutralizing both the earlier strain of virus as well as the mutant variant (D614G) that has emerged with greater infectivity, and now accounts for >80% of newly circulating virus
- No antibody-dependent enhanced disease events were reported
market will no doubt bounce around.  

http://ir.inovio.com/news-releases/news-releases-details/2020/INOVIOs-COVID-19-DNA-Vaccine-INO-4800-Provides-Protection-with-Memory-Immune-Responses-In-Non-Human-Primates-Challenged-with-SARS-CoV-2-Virus/default.aspx

Now we know that the mRNA based vaccines of Moderna and Pfizer require super-cooling freezers in transport and storage. Super cooling vaccines is just NOT practical if ones that do not require it are available.
 
 Messenger RNA cells ARE CREATED by the DNA
 
 I suspect that Moderna and Pfizer are doing it backwards and that Inovio's DNA approach will prevail as the better approach.

 __
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

Paul Harvey may have liked Inovio.

 

Market Talk

So since  we coined the term "the Biden effect" the overall market has seriously corrected with the Dow off over 1600 .  I suspect that at points during the next 55 days to the Nov 3 election, every time the balance seems to shift to a socialist Democrat victory - the overall market may just fade.  It will no doubt have bouts of optimism and dead cat bounces, but with a close election uncertainty will prevail and the market dislikes uncertainty.  High Taxes, tax and spend notions and socialism will change America as we know it.  Look at Venezuela.  Once one of the richest countries in Capitalism, that fell for socialism and is now a dictatorship called a Federal executive power. Once the richest country in South America now left poor starting with socialism leading to dictatorship.  Free stuff is not free.
 
 
 Stock Talk
 
The market will no doubt bounce around.  

 I think it is time to buy some Inovio back in my humble opinion.

 Why?  We see the new agreement with large American manufacturer for 100 mil doses of INO4800 should it gain FDA approval. It seems now that plans have been made for every person on the planet to have access to at least one of 100 Mil doses on INO4800 should it advance in FDA clinical trials and gain FDA approval.

We also see that Astrazeneca Oxford vaccine trial was halted to investigate a serious Adverse effect in a participant.  Was it really just one? I was not impressed with the reports on the Oxford vaccine.

Now we know that the mRNA based vaccines of Moderna and Pfizer require super-cooling freezers in transport and storage. mRNA vaccines have not been proven stable or durable after inoculation. Super cooling vaccines is just NOT practical if ones that do not require it are available.
 
So there are some apparent drawbacks in some of the Trump/ Fauci  operation warp speed team selections for funding.  Are they being dumb or conflicted with NIH patents on RNA? So far...

Now looking at Inovio's DNA based vaccine I have already posted here potential favorables. No super cooling required, long shelf life,
early Phase 1 and animal studies point to balanced antibodies, neutralizing and most importantly targeted fighter T cell immunity.

I have stated a key point that I believe the Trump OWS team and Fauci are missing when they selected mRNA vaccines for funding.

 Messenger RNA cells ARE CREATED by the DNA
 
 I suspect that Moderna and Pfizer are doing it backwards and that Inovio's DNA approach will prevail as the better approach.

 So with the fact that INO stock has been under recognized and abused by short sellers and all kinds of  "fool" pundits I have re established a position in some INO. One caveot - This is all my humble opinion .  I am back in "some INO shares" to see how it plays out going forward. I suspect things will improve for Inovio but only time and process will tell.

Please note !  how I use the word "some".  this is a speculative issue and I can generally say DO NOT put the farm on speculation.

In stocks and biotechs I apply cautious optimism when bullish because as I have learned "something always happens". INO is a trading stock to me but if I see affirmation I may "go long" on "some" as well.  The Inovio pipeline in DNA based Cancer treatments is  the Rest of the STORY as Paul Harvey  used to say.
 
So Spider J Jones signing off saying - watch INO.
 
and stay tuned for the Rest of the STORY.

__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___

Tuesday, September 8, 2020

Watching out for the "Biden effect" meanwhile stock talk on 2 stocks: NKLA and INO

 

Joe Biden can walk and talk at same time, look out below for awhile?

 

Market Talk

I am re-posting my last theory because I want to coin a name for it:
 
 "The Biden effect"
 
It's a name for Joe Biden can speak and what it can do to the market.  He has been coming out of his basement and showing that he can walk and talk at the same time. For those that have hatred for President Trump this bolsters the democrats hope.  The bar has been set low for  Biden thus far and as Trump haters say well at least Biden can speak and think so he's better than Trump,  the market may start anticipating that Biden may actually win and democrats sieze power.
 
If the Democrats do win, look out below as far as the market. High taxes and state bailouts to pay for mismanagement and such high debt  items such as state pensioners that drive typical democrat states like NJ and New York and California  into unsustainable debt.
 
The market is not ready for socialism and the burdening costs and taxes that it will require.  The market will not want America to be like Venezuela.
 
With the above preamble it seems like the run the market has had may stall and even falter as uncertainty about the election plays out and political positioning stall cooperation.  The vision for the  future of America is in the balance on Nov 3.

With regard to the oveall market?   Look out below for awhile?
 
 
 Stock Talk
 
Nikola (NKLA):  News today of a Nikola deal with GM on an electric truck.

 
 Inovio (INO) :  Inovio may still be in the mix in the vaccine race even though they have not yet received funding. However, the news today with a new partner to help produce 100 million doses in 2021 may be another "dot" to connect for Inovio.
 

As of today,  Inovio is a highly shorted company due to delays and short sellers.  "if" Inovio delivers excellent Phase 1 results on their clinical Covid 19 vaccine and advances as planned, Inovio may yet be a contender.
__ 
ALL in my humble opinion, scroll down and read more.. 

This site does NOT make Buy / Sell recommendations.
___